In a mixing bowl, combine the ground beef, garlic powder, onion powder, Italian seasoning, salt, and pepper. Mix until well blended.
Divide the mixture into four equal portions and shape them into patties, making a slight indentation in the center to prevent puffing during cooking.
Preheat the grill or a skillet over medium-high heat.
Cook the patties for approximately 6-7 minutes on each side, or until they reach an internal temperature of 160°F (71°C).
During the last few minutes of cooking, spoon marinara sauce over each patty, then top with mozzarella cheese, pepperoni, and olives if using. Cover to allow the cheese to melt.
Toast the burger buns on the grill or in a toaster.
Assemble the burgers by placing the patties on the buns, adding additional marinara sauce if desired, and garnishing with fresh basil leaves.
Serve immediately and enjoy!