Go Back
Cheesy Cajun Garlic Chicken Rotini Skillet Recipe taken with iphone 15 pro max --iw 2 --ar 4:5 --v 6.1 --raw

Cheesy Cajun Garlic Chicken Rotini Skillet

Creamy, spicy, and irresistibly cheesy—this Cheesy Cajun Garlic Chicken Rotini Skillet is a quick and comforting dinner perfect for weeknights. With bold Cajun flavor, tender chicken, and melty cheese, it’s a one-skillet wonder you’ll crave again and again.
Print Recipe Pin Recipe
Prep Time 10 minutes
Cook Time 20 minutes
Total Time 30 minutes
Servings 4 servings
Calories 720 kcal

Equipment

  • 1 Large Pot
  • 1 Large Skillet
  • 1 Mixing Bowl

Ingredients
  

Main ingredients

  • 2 pieces Boneless, skinless chicken breasts Cut into bite-sized chunks
  • 12 oz Rotini pasta
  • 2 tablespoon Olive oil
  • 2 tablespoon Cajun seasoning
  • 1 teaspoon Garlic powder
  • 1 teaspoon Onion powder
  • 1 teaspoon Salt
  • 1 teaspoon Pepper
  • 5 cloves Garlic Minced
  • 1 tablespoon Butter
  • 1 cup Heavy cream Room temperature
  • 0.5 cup Chicken broth Low-sodium preferred
  • 1 cup Shredded mozzarella cheese
  • 0.5 cup Grated Parmesan cheese
  • 0.5 cup Shredded cheddar cheese
  • 1 tablespoon Fresh parsley Chopped, optional for garnish

Instructions
 

Instructions

  • Bring a large pot of salted water to a boil. Cook the rotini according to package directions until al dente. Drain and set aside.
  • While the pasta cooks, combine Cajun seasoning, garlic powder, onion powder, salt, and pepper. Toss the chicken in the spice mix until evenly coated.
  • Heat olive oil in a large skillet over medium heat. Add the seasoned chicken and cook until browned and cooked through, about 8–9 minutes. Remove and set aside.
  • Reduce heat to medium-low. Add butter and minced garlic to the skillet. Sauté until fragrant, about 1 minute.
  • Pour in chicken broth and heavy cream. Bring to a gentle simmer, stirring to combine and scrape up browned bits.
  • Lower heat and stir in mozzarella, Parmesan, and cheddar cheese gradually. Stir until smooth and creamy. Thin with more broth or cream if needed.
  • Add rotini and chicken back to the skillet. Toss to coat in sauce. Simmer 2–3 minutes. Taste and adjust seasoning. Garnish with parsley and serve hot.

Notes

Refrigerate leftovers in an airtight container for up to 3 days. Freeze up to 2 months. Reheat in microwave or stovetop with splash of cream or broth to loosen sauce.